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SRF is at the center of the rejuvenation biotechnology industry and supports the mission to end age-related disease through Research, Education, and Outreach. Make your career something you can believe in – something that can change the world.

Career Opportunities

Job Opportunity: Research Associate / Scientist – Boominathan Lab (MitoSENS)

Job Type: Full-time
Number of Positions: 2
Title: Research Associate/Scientist – Boominathan Lab
Salary: Pay is salaried, commensurate with experience and local rates; typically from $55,000/year.

Qualifications:

  • Bachelor’s/Masters/PhD
  • Laboratory experience: 2 years (Preferred)

The Boominathan lab at SENS Research Foundation (www.sens.org) is hiring highly motivated Research Scientists / Associates for a project geared toward translational therapies for mitochondrial dysfunctions. SENS Research Foundation is located in the heart of Silicon Valley (Mountain View, CA) and is close to several premier research organizations and major biotech hubs. Ours is an exciting, cutting-edge non-profit organization dedicated to transforming the way the world treats aging. More detailed information can be found at http://sens.org/research/intramural/allotopic-expression.

The successful candidate will use in vitro, in vivo and stem cell models to address diseases due to mtDNA mutations. This research position is within a small but dynamic group that strives to develop a deep understanding and curative therapies using a gene therapy approach to treat mitochondrial myopathies. Qualified candidates will have a BS/MS in the biological sciences and at least 2 years of relevant work experience. Recent PhDs with an exposure to mitochondria biology will be considered for a Research Scientist position. Duties will include performing wet lab experiments, recording, and analyzing data, and presenting the results in formal meetings every 2-3 months.

The ideal applicant will have experience in tissue culture, microscopy, flow cytometry and molecular biology with an exposure to protein analysis and biochemical assays. Hands on experience working with rodents is highly desirable. Experience working with mitochondria or interest in protein modelling are a big plus, but not required.

Other qualities:

  • Problem-solving
  • Team player
  • Creativity and the ability to think beyond an experiment to envision the path to success
  • Capacity to adapt as priorities and requirements change
  • Ability to plan and document your work diligently
  • Excellent written and verbal communication skills in English
  • Positive spirit, a real drive for science

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. We may sponsor a visa for international applicants.

The positions are available now and will be filled as soon as qualified candidates are found. Salary is commensurate with job experience.

TO APPLY:

Interested candidates should apply by emailing a cover letter stating their scientific interests and current CV to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Job Opportunity: Postdoctoral Research Fellow – Catabody Project

Job Type: Full-time
Title: Postdoctoral Research Fellow – Catabody Project
Salary: Pay is salaried, commensurate with experience and local rates; typically around $60,000/year.

Qualifications:

  • Doctorate (Preferred)
  • Molecular biology: 2 years (Preferred)
  • Wet chemistry: 2 years (Preferred)

SENS Research Foundation (SRF) is hiring a postdoctoral research fellow for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats aging.

More detailed information can be found here.

We seek a postdoctoral fellow to join our small but dynamic immunology team led by Dr. Amit Sharma. The project geared towards developing a novel way to remove abnormal tau aggregation. The project is potentially relevant for developing therapeutic mitigation of normal age-dependent cognitive decline, as well as for tauopathies like Alzheimer’s Disease and Related Disorders. This project involves utilizing enzymatic antibodies to target toxic tau aggregates. As part of the project we will explore ways of delivering antibodies into cells. We will use human iPS derived neuronal cells as a model system to test the catalytic antibodies and confirm tau degradation. The project involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

Experience:

  • Ph.D. in chemical/biological sciences and substantial bench experience or several years of industry experience
  • immunology
  • antibody design/production/screening
  • general molecular biology techniques (such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA.)
  • iPSC culturing and neuronal differentiation

Other qualities:

  • Problem-solving
  • Team player
  • Creativity and the ability to think beyond an experiment to envision the path to success
  • Capacity to adapt as priorities and requirements change
  • Ability to plan and document your work diligently
  • Excellent written and verbal communication skills in English
  • Positive spirit, a real drive for science

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Job Opportunity: Research Associate – Catabody Project

Job Type: Full-time
Title: Research Associate
Salary: Pay is salaried, commensurate with experience and local rates; typically around $55,000/year.

Qualifications:

  • Master’s (Preferred)
  • Laboratory experience: 1 year (Preferred)
  • Wet chemistry: 1 year (Preferred)

SENS Research Foundation (SRF) is hiring a Research Associate for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a Research Associate to join our small but dynamic immunology team led by Dr. Amit Sharma. The project geared towards developing a novel way to remove abnormal tau aggregation. The project is potentially relevant for developing therapeutic mitigation of normal age-dependent cognitive decline, as well as for tauopathies like Alzheimer’s Disease and Related Disorders. This project involves utilizing enzymatic antibodies to target toxic tau aggregates. As part of the project we will explore ways of delivering antibodies into cells. We will use human iPS derived neuronal cells as a model system to test the catalytic antibodies and confirm tau degradation. The project involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial (or the master’s degree with at least 1-2 years) bench experience, industry experience position is preferred. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Job Opportunity: Postdoctoral Research Fellow – Senescence Immunology

Job Type: Full-time
Title: Postdoctoral Research Fellow – Senescence Immunology
Salary: Pay is salaried, commensurate with experience and local rates; typically around $60,000/year.

Qualifications:

  • Doctorate (Preferred)
  • Molecular biology: 2 years (Preferred)
  • Wet chemistry: 2 years (Preferred)

SENS Research Foundation (SRF) is hiring a postdoctoral research fellow for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a postdoctoral fellow to join our small but dynamic immunology team led by Dr. Amit Sharma for a project geared toward investigating the mechanisms involved in the age-dependent decline in immune surveillance of senescent cells with the aim of finding promising interventions.

There are three main projects currently for the postdoctoral fellow. One of the projects involves characterizing age-dependent phenotypes changes in the of Natural Killer cells and its implication on their ability to eliminate senescent cells in cell culture and mice model. We have identified several unique antigens expressed on the surface of senescent cells. The goal of the second project is to characterize the surface antigens on senescent cells and with the goal of developing CAR-NK cells with therapeutic application. The projects will require validating the CAR-NK cells in cell culture and the mice models of senescence. Senescent cells are known to secrete a unique mixture of proinflammatory cytokines, chemokines and matrix modifying proteins called SASP (Senescence Associated Secretory Phenotype). We have identified several SASP factors that may block immune surveillance by NK cells. The aim of the third project is to develop therapeutic interventions based on removal of these SASP proteins for enhancing immune surveillance of senescent cells in aging and senescence mice model. All these projects involve extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue.

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial bench experience. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. The prospective postdoc will work closely with the Primary Investigator (PI) on a couple of projects with the potential of landing senior authorships in research publications resulting from the work. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months. The candidate also will be encouraged to present their findings in relevant national and international conferences and relevant scientific journals.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Job Opportunity: Research Associate – Senescence Immunology

Job Type: Full-time
Title: Research Associate
Salary: Pay is salaried, commensurate with experience and local rates; typically around $55,000/year.

Qualifications:

  • Master’s (Preferred)
  • Laboratory experience: 1 year (Preferred)
  • Wet chemistry: 1 year (Preferred)

SENS Research Foundation (SRF) is hiring a Research Associate for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a Research Associate (RA) to join our small but dynamic immunology team led by Dr. Amit Sharma for a project geared toward investigating the mechanisms involved in the immune surveillance of senescent cells with the aim of finding promising interventions.

There are three main projects currently for the RA. One of the projects involves characterizing age-dependent phenotypes changes in the of Natural Killer cells and its implication on their ability to eliminate senescent cells in cell culture and mice model. We have identified several unique antigens expressed on the surface of senescent cells. The goal of the second project is to characterize the surface antigens on senescent cells and with the goal of developing CAR-NK cells with therapeutic application. The projects will require validating the CAR-NK cells in cell culture and the mice models of senescence. Senescent cells are known to secrete a unique mixture of proinflammatory cytokines, chemokines and matrix modifying proteins called SASP (Senescence Associated Secretory Phenotype). We have identified several SASP factors that may block immune surveillance by NK cells. The aim of the third project is to develop therapeutic interventions based on removal of these SASP proteins for enhancing immune surveillance of senescent cells in aging and senescence mice model. All these projects involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue.

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial (or the master’s degree with at least 1-2 years) bench experience, industry experience position is preferred. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Job Opportunity: Laboratory Manager

Job Type: Full-time
Title: Laboratory Manager
Salary: Pay is salaried, commensurate with experience and local rates; typical range $55,000-60,000/year.

SENS Research Foundation (SRF) is hiring a Laboratory Manager for our research center located in Mountain View, Silicon Valley, CA. SRF is a non-profit organisation globally recognized for its dedication to transforming the way the world researches and treats aging (www.sens.org)

The research center hosts the SRF internal research and affiliated initiatives including SRF spinout Underdog Pharmaceuticals. Our ca. 20 lab members include postdoctoral specialists as well as student researchers. The Laboratory Manager will provide daily support, supervision and coordination at every level to ensure the smooth running of all laboratory research.

The ideal candidate is a person that loves an orderly lab and rises to the challenge of changing requirements of cutting edge science. You need to be able to work independently and set your own tasks and priorities but communicate consistently and effectively with all laboratory personnel, nurturing lab cohesiveness and team spirit.

KEY RESPONSIBILITIES:

  • organize and oversee the daily operation of the research lab
  • inventory management, ordering and purchasing of research consumables (including effective negotiations with suppliers and service providers)
  • conduct regular maintenance of equipment
  • oversee general adherence to good animal husbandry (rodents)
  • mentor and supervise new staff in standard laboratory procedures
  • maintain a clean, safe laboratory and hold people accountable
  • regular and project-specific reporting to the VP (research)
  • develop and implement appropriate administrative policies and procedures for the laboratory
  • as required by research leads from time to time: assist with experiments, data entry and analysis

QUALIFICATIONS: required

  • a first or advanced degree in Biology, Biochemistry, Chemistry or related field
  • 5+ years’ laboratory experience
  • experience in research-related supervision, training or teaching
  • good interpersonal, written and verbal communication skills
  • advanced familiarity with MS Excel and similar applications
  • ability to maintain complete and organized records/reports
  • proven ability to organise cost-effective procurement

QUALIFICATIONS: desirable

  • Experience running and maintaining HPLCs
  • Experience in running automated microscopy
  • Experience with animal (rodent) husbandry
  • Experience with flow cytometry
  • Experience in running cell culture
  • Experience with RT-PCR
  • Experience with lab procurement software (e.g. Quartzy)
  • Knowledge of aging biology

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found.

TO APPLY:

Please submit your CV along with a Cover Letter to [email protected].

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

Please check back soon for more career opportunities.

Students

Current undergraduate students and recent graduates, respectively, can apply to the annual Summer Scholar and Postbaccalaureate Fellowship programs run by SRF Education. These programs are the best way for early-career researchers to get involved with research in rejuvenation biotechnology.

Volunteers

We don’t regularly use volunteers, but if you would like to be added to our Volunteer Directory then contact us to register your interest. To assist us in matching you with future opportunities to help, please include a brief summary of any specific skills or resources you’d be able to offer in support of our mission.

Research Collaborators

If you are a research scientist working in a SENS-related field, you may wish to submit a grant proposal for consideration by our Research Development Committee.

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