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Help us Fight Aging with Our Anti-Senescence Discovery
Abdelhadi Rebbaa, PhD
Aging is a risk factor for many chronic and terminal diseases. The accumulation of senescent cells in the body over time is a major cause of aging. The RepleniSENS team at SENS Research Foundation is working on identifying therapeutics that reduce senescent cell accumulation in our bodies and extend our health span. By supporting this project, you will help accelerate the creation of a novel arsenal of weapons to combat aging and prevent age-related chronic diseases. Donate for more health!
Goals of the project:
As a model to study senescence in a dish, we will use a type of healthy cells that emit light when they are induced into senescence. This assay will allow us to assess relatively quickly the efficacy of therapeutic candidates that inhibit senescence.
By using this cellular model and in order to increase our chance of finding effective anti-aging candidates, we will screen a large library of compounds for their ability to delay senescence.
We have already established and validated this assay in our laboratory, and we are ready to start the screening. This process is expected to last about 6 months. The identified candidates will be considered in future studies for rigorous preclinical and clinical testing.
