Replacing Lost Cells

2022 End of Year Campaign


Challenging Parkinson's

No Damage Left Unchallenged!​


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*If you are donating via cryptocurrency or NFT and would like to vote on which strand should receive a RFP for 2023, please send us an email address we can associate with your donation so that we can issue voting tokens to you.

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…then use your tokens to vote – and the strand with the most support will receive a new RFP (Request for Proposals) for 2023!

Why RepleniSENS:

Life begins with the cell, and ultimately it ends with them. Throughout our lives, we’re losing cells for one reason or another. Some cells are destroyed by trauma or being cut off from their blood supply. Some are designed to slough off, like outer skin cells and cells on the surfaces of our GI tract. And some self-destruct after they’ve served their purpose or if they sense themselves to be in danger of becoming cancerous. For many of these cells this is no big deal: they’re more or less interchangeable and the body easily replaces them. But others are hard to replace — or they become hard to replace due to aging changes in the organ. Meanwhile, the stem cells that are supposed to replace them can themselves become depleted due to aging processes. And there are a few critical cells (like most brain neurons and heart muscle cells) that don’t get replaced at all: they’re designed to last a lifetime, but not the kind of lifetime we live today or want to live in the future. Support RepleniSENS, and bring back what you’ve been missing!

RepleniSENS: Ask Me Anything:

With Dr. Abdlelhadi Rebbaa & Michael Rae

With Dr. Jean Hébert & Michael Rae

This week's Life Noggin video:

Disease Focus: Parkinson's

The most recognizable signs of Parkinson’s disease — the hand tremors, the stony face, the loss of balance — are the result of the loss of a specific kind of nerve cell in a specific region of the brain. These neurons are responsible for producing the brain messenger-molecule dopamine and delivering it in a precisely controlled way to a region of the brain involved in motion control. As we age, all of us gradually lose these cells, and some people lose them more quickly because of genetics or lifestyle and environmental factors. When our reserve of these cells falls below a critical threshold, the remaining cells can no longer properly guide the motion center. Our fine control of our motion degrades, and our hands begin to tremble. The symptoms worsen over time as more neurons are lost, and the drugs used to control symptoms become less and less effective and harder and harder to manage.

Scientists have worked for decades on RepleniSENS therapies for people suffering with Parkinson’s, and it’s been a learning process: some patients in these trials have benefitted hardly at all, but others have had remarkable recoveries that free them from drugs for years. They are now working on new trials, using the powerful new biotechnology of cellular reprogramming  create custom cells of just the right kind, and using new surgical techniques to deliver them to just the right place. Support RepleniSENS so we’ll all move freely again!

Watch the RepleniSENS approach animation:

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