
To Save Your Brain, Slay The Zombie (Senescent) Cells!
Michael Rae discusses the role of senescent cells in the brain during aging, and how eliminating those cells could prevent diseases like Alzheimer’s and Parkinson’s.
The SENSible Blog discusses the development of rejuvenation biotechnology around the world: progress being made in the field of longevity, the design of medical therapies to cure, reverse and prevent the diseases and disabilities of aging, and much more.
Our content is a blend of popular interest articles – labelled “Easy Reads”, and designed to require no specific background knowledge – as well as more detailed scientific commentaries, labelled as “In-Depth” and aimed towards readers with some grounding in the biological/medical sciences.
Michael Rae discusses the role of senescent cells in the brain during aging, and how eliminating those cells could prevent diseases like Alzheimer’s and Parkinson’s.
Article by Michael Rae about recent and forthcoming regulatory reforms required to support the testing of new therapies for Alzheimer’s and other age-related diseases.
Question Of The Month #16: Any Rejuvenation Relevance for Roundworm Reproduction? Part of Michael Rae’s regular column from the Foundation’s newsletter.
Alpha-synuclein aggregates are a key form of aging damage in the brain, linked to a spectrum of symptoms in Parkinson’s disease beyond the classic motor symptoms. The first amyloSENS-style immunotherapy to clear this pathology out of the brain was advanced into clinical trials by Austrian biotech firm AFFiRiS AG. Now two more such therapies have entered human testing. Although the trials are in their earliest stages, they bring the hope that this rejuvenation biotechnology will begin preventing and reversing Parkinson’s disease and less specific disorders of aging soon.
Question of the Month #15: Would Other Rejuvenation Biotechnologies Keep Us Cancer-Free? Part of Michael Rae’s regular column from the Foundation’s newsletter.
Question of the Month #13: How Can Thymic Regeneration Combat Age-Related Autoimmunity? Part of Michael Rae’s regular column from the Foundation’s newsletter.
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