Mitochondrial function declines with age, and these dysfunctional mitochondria adversely contribute to several metabolic and neuromuscular diseases. The mitoSENS team is working tirelessly to help discover the science to reverse and/or prevent damage to mitochondrial DNA.
The SENS team is developing an innovative approach to repair mitochondrial mutations that, if successful, will have demonstrated, for the first time, a mechanism that can provide your cells with a modified backup copy of the entire mitochondrial genome. This genome would then reside within the protective confines of the cell’s nucleus, thereby mitigating damage to the mitochondrial genome.
Demonstrating the effectiveness of this technology would be a major milestone in the prevention and reversal of aging in the human body and it will also help address mitochondrial disease that affects people of all ages, including children born with mutations in this mtDNA.
Learn more about our project and team here: Engineering New Mitochondrial Genes to Restore Mitochondrial Function MitoSENS