SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.

Discover the science behind our strategies to extend a healthy lifespan.

Training a new generation of scientists to tackle the roots of age-related disease.

Keep up to date on SRF’s latest news and activities.

We are proud to have sponsored RAADFEST for another consecutive year and to have had some of our key team members presenting at the event.

RAADfest is the world’s largest gathering of radical life extension enthusiasts. RAADfest combines the energy and fun of a festival, the empowerment and interaction of personal development, with cutting edge science presented for a lay audience to create the most holistic radical life extension event ever.

You can view our SRF presenters, as well as a wide variety of speakers from all areas of the life extension community here:

We are pleased to announce that the ApoptoSENS team led by Dr. Amit Sharma at the SRF Research Center has recently been granted a Catalyst award, courtesy of the Healthy Longevity Global Competition, to continue and expand their critical work on the interactions between senescent cells and natural killer (NK) cells.

Supported by the award, the ApoptoSENS team will now investigate whether the age-related loss of NK cell effectiveness in clearing senescent cells is reversible, and whether this may provide routes for therapeutic intervention. If successful, this work will clear a major hurdle to realizing NK cell-based treatments for senescent cell elimination.

The Research-Integrated Science Education (RISE) Program has launched a new cellular senescence-themed learning module. Explore videos detailing laboratory techniques and biological concepts underpinning cell senescence research to better understand SRF’s current project led by Dr. Amit Sharma.

Teachers will also be able to utilize additional resources, such as presentations outlining primary literature and interactive data analysis activities, to explore how senescence affects lifespan, cancer, and Alzheimer’s Disease.

The News:

NIA Reports Senolytics Show Potential to Protect Against Coronavirus in Older Mice

The NIA reports: “Cellular senescence, an aging mechanism in which cells lose normal function, may contribute to a worse response in human cells to COVID-19 and in older mice to a similar coronavirus — but a class of drug known as senolytics decreased adverse responses and increased survival for the mice. The preclinical findings from a study funded in part by NIA were recently published in Science.”

This is also the focus of one of SRF’s projects that is working on selectively removing senescent cells and reversing the damage caused by them to rejuvenate the immune system.

SENS Research Foundation wishes you Happy International Longevity Day and Longevity Month!

The United Nations General Assembly voted to establish October 1st as the ‘International Day of Older Persons’ as recorded in Resolution 45/106. The holiday was observed for the first time on October 1st, 1991.

Following this tradition, longevity research activists from around the world call this day and the month of October; International Longevity Day and International Longevity Month.

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