SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.

Discover the science behind our strategies to extend a healthy lifespan.

Training a new generation of scientists to tackle the roots of age-related disease.

Keep up to date on SRF’s latest news and activities.

SENS Research Foundation is delighted to announce the release of our latest Annual Report, describing the progress of our work through 2019-2020.

The report includes sections on all of our active research projects and our outreach efforts around the world, introduces some new additions to the SRF team, and includes a tribute to founding CEO Mike Kope as well as details on his new position leading SRF spin-off Underdog Pharmaceuticals.

As ever, we’re tremendously grateful to the supporters whose donations have enabled us to make these steps towards a world free of age-related disease and disability.

We’re delighted to announce that SRF’s Chief Science Officer Dr. Aubrey de Grey has been awarded the 2020 Bacon Prize for Thought Leadership in Super Longevity at this year’s RAADfest.

Organized by the Coalition for Radical Life Extension, the Bacon Prize is named for both Roger Bacon and Sir Francis Bacon – who, though they lived centuries apart, both made pioneering contributions to addressing aging as a tractable medical problem through the development of empirical testing and scientific methodology.

Michael Antonov donated $400,000.00 to SRF outright at the beginning of our campaign, then set up a matching grant of up to $600,000.00 for our supporters to match. His generosity and vision for our cause encouraged eleven other supporters of SRF to turn his offer of doubling donations into a triple donation. The first $525,000.00 of support we received was tripled, and we are thrilled to announce that the full $600,000.00 of the original match was met. SRF raised a total of $2,335,443.46 in this year’s campaign.

We are pleased to announce that the ApoptoSENS team led by Dr. Amit Sharma at the SRF Research Center has recently been granted a Catalyst award, courtesy of the Healthy Longevity Global Competition, to continue and expand their critical work on the interactions between senescent cells and natural killer (NK) cells.

Supported by the award, the ApoptoSENS team will now investigate whether the age-related loss of NK cell effectiveness in clearing senescent cells is reversible, and whether this may provide routes for therapeutic intervention. If successful, this work will clear a major hurdle to realizing NK cell-based treatments for senescent cell elimination.

SRF is now accepting applications for the 2021 Postbaccalaureate Fellowship Program.

Submit an application to join one of the many exciting research projects that will train you as a regenerative medicine scientist.

The latest SRF news:

Antonov Foundation donates $1M to SRF’s End of Year Campaign

At the end of each year, SRF launches our final fundraising campaign – the aptly named End of Year Campaign – to encourage our donors to donate during the most giving time of year. This year, matching funds from Michael Antonov and a team of other supporters helped you to smash through our original goal.

Parabiosis: the Dilution Solution?

In heterochronic parabiosis, joining the circulatory systems of young and old mice causes the older animal to recover some features of youth. The effect has been widely assumed to be driven by pro-youth factors in younger blood, but an alternative hypothesis is possible: that the procedure is instead diluting pro-aging factors in the older partner.

Send In The Senolytics

Elie Dolgin’s recent article in Nature Biotechnology explains why the failure of the first senolytic drug to enter clinical trials is far from being a refutation of the senolytic hypothesis, and reviews the growing arsenal of other senolytics currently in development – including work by SRF’s Dr. Amit Sharma and SRF-supported startup Oisín Biotechnologies.

2012 SRF Summer Scholar Profile: Ali Crampton

Ali will receive her B.S. in Biomedical Engineering from the University of California at Irvine in June 2013 after just three years of study. She worked in the Cardiopulmonary Transport and Tissue Remodeling Laboratory at UCI starting as a freshman,

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2012 SRF Summer Scholar Profile: Nick Schaum

Nick received his B.S. in Biological Sciences from Virginia Tech in May 2013. As an undergraduate, he worked in Dr. David Bevan’s molecular modeling laboratory studying the accumulation of amyloid beta, a protein that plays an important role in the

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2012 SRF Summer Scholar Profile: Sam Curran

Sam received his B.S. in Environmental Biology from The State University of New York (SUNY), College of Environmental Science and Forestry (ESF) in Syracuse, NY. As an undergraduate, Sam engaged in a wide variety of research projects. He investigated the

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