We Are Building a Future Free of Age-Related Disease

SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.

Discover the science behind our strategies to extend a healthy lifespan.

Training a new generation of scientists to tackle the roots of age-related disease.

Keep up to date on SRF’s latest news and activities.

Outreach Highlights -

Watch Lifespan.io Executive Director and SENS Research Foundation Chief Business Officer Stephanie Dainow lead a panel entitled Longevity: How Programmable Biology is Helping Humans Live Healthier & Longer at the SALT iConnections Conference in New York City.

This panel explores the concept of longevity within the scope of programmable biology, discussing advancements such as early disease detection, engineered immunity, and cellular rejuvenation as means to extend healthy lifespans. 

SENS Research Foundation, dedicated to advancing rejuvenation biotechnologies, has recently begun subleasing lab space in the heart of Silicon Valley.

The sublease includes access to an extensive list of laboratory equipment, a break room, conference rooms, and much more.

Research Highlights -

Watch SRF Science Writer Michael Rae‘s presentation Damage Repair is the Superior Approach Against Aging.

SRF is a proud sponsor of the Phaedon Institute’s Seno-Therapeutics Summit 2023. Dr. Amit Sharma spoke at the Summit – his presentation was entitled, “Next-generation Senotherapeutics: From harnessing the immune system to targeting newer vulnerabilities of senescent cells.

The summit was hosted by the Buck Institute For Research On Aging in Novato, CA. Entitled Seno-Therapeutics: Past, Present & Future of the Science of Cellular Senescence and Therapeutics, the summit was held November 7-8, 2023.

Education Highlights -

Thank you to Stanford University for allowing us to participate at this year’s Biosciences virtual career fair. 

Thank you to Dr. Matt Kaeberlein and Michael Rae for their seminars to our SRF staff and students this past month.

Welcome to our new Summer Scholars and Post-Baccalaureates for this upcoming term!

Matt Kaeberlein, Ph.D., CEO of Optispan, Adjunct Professor of Oral Health Sciences at UW, and Co-Director of the Dog Aging Project presented  Longevity Science: From Molecules to Pets to Clinical Practice.


Get the Message: mRNA to Target Intracellular Aggregates

Several pharma companies are currently running clinical trials on damage-repair therapies targeting damaged forms of the protein tau to combat Alzheimer’s disease. But these AmyloSENS therapies only reach tau in the fluid outside of neurons, when what we need is to clear damaged tau inside of them. Fortunately, researchers are beginning to use mRNA — the same revolutionary biotechnology platform of the best COVID vaccines — to develop new LysoSENS therapies to do just that.

Viva Viagra? Firmer Methodologies Needed

A recent preprint reports that use of Viagra and related drugs is associated with a lower mortality rate, raising hopes that it might be repurposed as a longevity therapeutic. Unfortunately, the methodology used in this and other recent studies is too weak to arouse too much excitement just yet.

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