SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. We are redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists.

Discover the science behind our strategies to extend a healthy lifespan.

Training a new generation of scientists to tackle the roots of age-related disease.

Keep up to date on SRF’s latest news and activities.

May 13-15, Berlin.

The conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control.

2019’s event attracted nearly 500 participants from over 30 countries. Undoing Aging 2021 will once again bring together global pioneers who are leading the charge in maintaining and restoring full health in old age.

To accommodate the exciting growth of the rejuvenation biotechnology industry, Undoing Aging 2021 will host a dedicated forum and exhibition space for startups to present themselves to prospective investors and partners — while a special “Rejuvenation Now” session will highlight the human rejuvenation therapies that are currently in clinical trials or are available today.

Nearly half of the mammalian genome is long and short interspersed virus-like repetitive elements (LINEs and SINEs), which spread through the process of retrotransposition.

SRF is funding a study to test the impact of the removal of cells damaged by LINE/SINE reactivation on healthspan and lifespan, via the creation of a special transgenic mouse in the lab of Dr. Andrei Gudkov at the Roswell Park Comprehensive Cancer Center.

Since 2012, SRF Education has supported over a hundred students through funded placements at research institutions around the world. Our programs emphasize the development of both laboratory and communication skills to develop well-rounded future scientists, healthcare professionals, and policy makers.

Under the guidance of a world-class scientific mentor, each participant is responsible for his or her own research project in areas relevant to SENS Research Foundation’s mission to cure and prevent the diseases and disabilities of aging.

We’ve collected their accounts of their experiences and accomplishments in a new gallery page – take a look!

The latest SRF news:

Which Links Must Be Broken?

Dr. Jonathan Clark’s SRF-funded group at the Babraham Institute have published two new papers showing that the current model in which aging tissues lose elasticity due to the accumulation of stable crosslinks is not the full story – results which will be crucial to reversing that deterioration.

New 2020 Publications

2020 has already seen six new SRF-supported papers – including validation of a key tactic to prevent mitochondrial aging by our MitoSENS team, and an in-depth review coauthored by SRF, Underdog Pharmaceuticals and professor W. Gray Jerome on the major LysoSENS target 7-ketocholesterol.

Staging Aging

A team including SRF protégé Stuart Calimport and several members of our Research Advisory Board argues in Science that the systematic classification and staging of aging-related pathology (as is currently done for cancer) should dramatically accelerate the deployment of rejuvenation therapies.

SciFuture Interview

In conversation with Adam Ford, Dr. Aubrey de Grey explains how recent extraordinary results with senolytic drugs suggest that the milestone of “Robust Mouse Rejuvenation” – a key step towards comprehensively undoing human aging – could be as little as three years away.

Read More »

More Cryptocurrencies Added

SENS Research Foundation is now able to accept donations in Zcash (ZEC), in addition to eight other major cryptocurrencies: Bitcoin, Bitcoin Cash, Ethereum, Ethereum Classic, Litecoin, 0x (ZRX), USD Coin, and BAT. Visit the donate page for more information!

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Vitalik’s $350,000 Donation

We’re grateful to cryptocurrency pioneer Vitalik Buterin for once again choosing to support SENS Research Foundation, with a generous donation of $350,000 in Ethereum towards our End of Year campaign to Reimagine Aging.

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