LysoSENS - Reversing Heart Disease
This video, narrated by actor Edward James Olmos, describes the process that causes heart disease and highlights a promising intervention that SENS Research Foundation is funding. The video begins with an explanation of cholesterol particles that can become trapped in blood vessels and the patrolling macrophages that normally remove them. However, the macrophages struggle to process oxidized cholesterol. This problem causes the macrophages to die, and the resulting foam cells form atherosclerotic plaques, which ultimately cause heart attacks and strokes. SRF is funding research into an enzyme that would enable macrophages to degrade these oxidized cholesterol particles, thereby rescuing the macrophages, preventing plague buildup, and possibly even reversing the atherosclerotic process.