The Forever Healthy Foundation Fellowship in Rejuvenation Biotechnology

Posted by SENS Research Foundation on March 08, 2018 | SRF Research

In cooperation with the Forever Healthy Foundation, SENS Research Foundation (SRF) is inviting candidates to submit research proposals for a Fellowship in Rejuvenation Biotechnology at our Research Center (RC) in Mountain View, California.

2013 Research Report (Part 7 of 12): Extracellular Aggregates

Posted by Iain Inkster on January 06, 2014 | SRF Research

University of Texas, Houston TX, and Brigham and Women’s Hospital, Harvard University, Boston MA Researchers: Sudhir Paul, Yasuhiro Nishiyama, Stephanie Planque (University of Texas); Brian O’Nuallain (Brigham and Women's Hospital, Harvard Medical School)

2013 Research Report (part 6 of 12): Epimutations

Posted by Iain Inkster on December 05, 2013 | SRF Research

Albert Einstein College of Medicine (AECOM), Bronx NY Researchers: Jan Vijg, Silvia Gravina

2013 Research Report (Part 5 of 12): Lysosomal Aggregates

Posted by Iain Inkster on November 08, 2013 | SRF Research

Researchers: Pedro Alvarez, Jacques Mathieu, Jason Gaspar

2013 Research Report (part 4 of 12): Extracellular Matrix Stiffening

Posted by Iain Inkster on November 01, 2013 | SRF Research

Our arteries slowly stiffen with age, in substantial part because of chemical crosslinking of their structural proteins by blood sugar and other fuels in the circulation. Like the crosslinking that causes rubber windshield wipers to become stiff and brittle over time, the crosslinking of arterial proteins with age leaves us with increasingly rigid blood vessels...

2013 Research Report (part 3 of 12): Cancerous Cells

Posted by Iain Inkster on October 18, 2013 | SRF Research

Researchers: Haroldo Silva, David Halvorsen, Kelsey Moody, Thomas Hunt

2013 Research Report (part 2 of 12): Mitochondrial Mutations

Posted by Iain Inkster on October 09, 2013 | SRF Research

Researchers: Matthew O'Connor, Amutha Boominathan, Jayanthi Vengalam

2013 Research Report (part 1 of 12): Lysosomal Aggregates

Posted by Iain Inkster on September 01, 2013 | SRF Research

Researchers: Gouri Yogalingam, Ghezal Beliakoff, Ehud Goldin, Maximus Peto

Amutha Boominathan: Moving vulnerable mitochondrial genes to the safety of the nucleus

Posted by iain.inkster on July 24, 2013 | SRF Research

We all know that mitochondria are the cell's "powerhouse" for energy. One interesting fact about these organelles is that they have their own DNA in addition to the nuclear DNA that we are all aware of. However, the mitochondrial DNA is prone to mutations due to constant exposure from reactive oxygen species because it is not encased in a nuclear envelope nor does it have efficient repair mechanisms to correct mutations as they occur. Amutha Boominathan explains how moving the mitochondrial genes to the nucleus, where it's safer to express them for function, would let mitochondria keep producing energy normally, even after mitochondrial mutations have occurred.

Jayanthi Vengalam: Engineering backup mitochondrial genes

Posted by iain.inkster on July 20, 2013 | SRF Research

Jayanthi Vengalam explains her work with the Mitochondrial Mutation team, with consequences for acute diseases such as diabetes, Parkinson's and Alzheimer's