The Potential Application of Real Time Release Testing for the Biomanufacture of Autologous Cell Based Immunotherapies.

BioProcess International. 13(4):1-8.

The Potential Application of Real Time Release Testing for the Biomanufacture of Autologous Cell Based Immunotherapies.

Brindley DA, Rekhi R, Fuerstenau-Sharp M, Kantoff PW, Hollander GA, Smith JA, Tindal S, Timmins N, Bure K.

Abstract

Abstract:

Cell-based immunotherapies (iTx) are emerging as a truly transformative therapeutic modality that is both complementary and convergent with existing regenerative medicine approaches, including gene therapy, cell therapy, and tissue engineering. Critically, iTx offer step-change improvements in efficacy compared with current standards of care for a range of clinical indications and unmet therapeutic needs — particularly oncology.