J.C. Guerin

Field observations have suggested for quite some time that certain fish, turtles and invertebrates have extremely long maximum lifespan potential. Age validation techniques have since confirmed these observations. Negligible senescence is defined in part as no observable age-related increase in mortality rate or decrease in reproduction rate after maturity, and no observable age-related decline in physiological capacity or disease resistance. Recent data compiled on rockfish (genus Sebastes) have documented ages exceeding 200 years but also many species under 30 years maximum observed lifespan, raising the intriguing possibility of intra-species lifespan comparison. The Centenarian Species and Rockfish Project has 14 total pilot studies. The three studies reported in this poster are: "Rockfish liver microarrays using existing 16,000+ zebrafish gene chips", a collaboration between Glenn S. Gerhard, Dartmouth Medical Center, and Renee Malek, TIGR (The Institute for Genomic Research); "Heat Shock Protein comparison between younger and older rockfish", Marcelle Morrison-Bogorad, Associate Director, Neuroscience and Neuropsychology of Aging Program, NIA; and "Electron transport abnormalities and mitochondrial DNA mutations in rockfish heart tissue", Judd Aiken, University of Wisconsin-Madison.

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