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Platinum Sponsors
A primary reason that we grow old and our health declines might be that a region of our DNA called the “telomere” shortens every time our cells divide. An enzyme called “telomerase,” produced within our cells, can re-lengthen our telomeres. All human cells have a gene that produces telomerase, but it is inactive in the vast majority of our cells. Over the last two decades, scientists have established that telomere shortening may play a role in nearly every disease associated with old age, from heart disease to arthritis to cancer. Support-of-concept experiments at three independent laboratories have also suggested that turning on telomerase causes age reversal effects in human cells and mice. Dr. Bill Andrews founded Sierra Sciences in 1999 to pursue the possible anti-aging applications of turning on the telomerase gene, to find out if telomeres really play a role in aging and disease. Formerly, he was the Director of Molecular Biology at Geron Corporation, where he and his team won second place for National Inventor of the Year for discovering human telomerase. From 1999 to 2006, Sierra Sciences studied and characterized the potential regulatory mechanisms of the telomerase gene and discovered several genetic sites and strategies for turning it on. In 2007, Sierra Sciences discovered its first small-molecule, drug-like compound, called C0057684, that could turn on the telomerase gene in human cells. The discovery of C0057684 led to the development of a very accurate, proprietary, high-throughput screening system, which in turn led to the discovery of even more powerful compounds that turn on telomerase. Sierra Science is truly interested in finding a cure for aging. The company is endeavoring to search for stronger and stronger telomerase inducers until it finds a compound potent enough to lengthen telomeres, not just decrease their rate of shortening. Once that has been achieved we can then ask the BIG questions: Does telomerase stop or reverse human aging and declining health? Are there negative effects of producing telomerase, such as cancer?
Silver Sponsors
Since 1991 International Antiaging Systems (IAS), has offered many unique anti-ageing products and services based on the belief that access to the world’s latest commercially available substances should be easier. If you are looking for unique, evidence based health products from around the world, IAS is your number one resource. Contact us today to get a free year’s subscription to the Aging Matters™ magazine worth $48.
Bronze Sponsors
How do you put a compound into food that will degrade there in a matter of hours? You engineer yogurt bacteria to produce it. We are calling it the “Youngurt” and it’s a small nutriceutical factory for your fridge. Taste our life-extending, SAM and spermidine producing prototype!
Life Extension® has been at the forefront of medical research for over 35 years, seeking ways to prolong youth, health, and life. To date we have invested over $140 million to find therapies and technologies that could lead to cures for age-related diseases. Over the years, we’ve introduced a remarkable number of groundbreaking products to the marketplace. All Life Extension products are based on the latest scientific studies and offer efficacious ingredients at clinical doses. Our focus is on quality, purity, and potency.
Since 1988, PeproTech has grown into a global enterprise manufacturing an extensive line of Recombinant Human, Murine and Rat Cytokines, Animal-Free Recombinant Cytokines, Monoclonal Antibodies, Affinity Purified Polyclonal Antibodies, Affinity Purified Biotinylated Polyclonal Antibodies, ELISA Development Kits, Cell Culture Media Products and GMP Cytokines.
Media Sponsors
Rejuvenation Research publishes cutting-edge research on rejuvenation therapies in the laboratory and clinic. The Journal delivers the latest information on the molecular and cellular mechanisms necessary for these therapeutic approaches to be most effective, and provides key explorations and advances that may ultimately contribute to slowing or reversing the aging process.