Replacement of lost and damaged cells remain critical to the repair of age related damage and associated pathology. Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of blastocysts and have the ability to differentiate into any cell type in an adult organism. It has been 30 years since the isolation and culture of mouse ESCs and 13 years since the similar isolation and culture of human ESCs. Despite these time-frames low-hanging fruit in the development of viable cell therapies based on ESCs remain abundant. Specific stepwise strategies on the realization of ESC based rejuvenation biotechnology are presented for the purpose of stimulating discussion on its implementation.
embryonic stem cell