Abstract Archive

This searchable list includes the abstracts of all presentations given at a conference organised as part of the SENS series. We regret that the videos recorded at SENS3 and SENS4 are currently unavailable.

Engineering anti-cancer T cells

Authors: R.E. Hawkins

Using our knowledge of tumour immunology and genetic technology to treat cancer is now a realistic possibility. There are a variety of potential approaches but adoptive transfer of tumour-specific T cells is currently the most effective and has been successful in treating advanced melanomas. To extend this to other cancers and to simplify the process for clinical use, Engineered T cells (gene modified T cells artificially endowed with anti-cancer specificity) have been developed.

Keywords: cancer immunotherapy, T cells, retrovirus, autoimmunity,