Infection-mimicking materials to program dendritic cells in situ (CANCELLED)
Organiser's Note: This talk was cancelled by the presenter, and therefore no video is available.
Cancer vaccines typically depend on cumbersome and expensive manipulation of dendritic cells in the laboratory, and subsequent cell transplantation leads to poor lymph-node homing and limited efficacy. We have demonstrated that materials mimicking key aspects of bacterial infection may instead be used to directly control dendritic cell trafficking and activation in the body to promote therapeutic, antitumor immune responses.
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