Thanks to the prodigious efforts of Richard Schueler (who supervised the recordings, provided the camera and edited the files), splendidly assisted by Irvin Bussel and Stuart Calimport (who did most of the actual filming), we are able to provide both audio and video recordings of most of the talks at SENS3. The links below are to audio recordings of each of the talks whose presenters did not ask us to keep them private.

Thursday 6th September
Session 1: Emerging pharmaceutical interventions in aging (Chair: Arne Akbar)
13:35	Patrizia D'Alessio Paris, France	AISA ("Anti-Inflammatory Senescence Actives") 5203-L molecule to promote healthy aging and prolongation of lifespan
14:05	Laura Dugan La Jolla, USA	Fullerene-based nanotechnology: developing strategies to study and treat oxidative stress in aging
14:35	Randy Strong San Antonio, USA	Video not available
15:05	Pierre Moreau Montreal, Canada	Can we influence the "normal" aging of arteries?
15:35	Steve Coles Los Angeles, USA	Secrets of the oldest old
15:50	Coffee
Session 2: Immunotherapy against cancer (Chair: Patrizia d'Alessio)
16:10	Zheng Cui Winston-Salem, USA	From a newly discovered innate anticancer immune response in mice to a new treatment for human cancers
16:40	Robert Hawkins Manchester, UK	Engineering anti-cancer T cells
17:10	Claudia Gravekamp San Francisco, USA	Efficacy of cancer vaccines to prevent cancer in the elderly
17:40	Coffee
Session 3: Persistent viruses in aging and Alzheimer's disease (Chair: Claudia Gravekamp)
18:00	Ruth Itzhaki Manchester, UK	Herpes simplex virus type 1 in brain is a cause of the neuropathological features of Alzheimer's disease
18:30	Edward Mocarski Atlanta, USA	Virus modulation of cell death pathways
19:00	Noel Patton for Rita Effros Los Angeles, USA	Nutraceutical telomerase stimulation with TA-65
19:30	Arne Akbar London, UK	Retarding immune senescence and reducing infections in ageing
20:00	Dinner
21:00	Welcome reception and Poster session 1
Friday 7th September
7:30	Breakfast
Session 4: Combating neurodegeneration (Chair: Pedro Alvarez)
8:30	Elizabeth Corder Durham, USA	Video not available
9:00	Jason Emsley (Macklis lab) Cambridge, USA	Video not available
9:30	Rutledge Ellis-Behnke Cambridge, USA	Using nanotchnology to repair the body
10:00	Cynthia Lemere Cambridge, USA	Cerebral amyloid-beta protein accumulation with aging in cotton-top tamarins: a model of early Alzheimer's disease?
10:30	Coffee
Session 5: Damage to long-lived intracellular molecules (Chair: Cynthia Lemere)
10:50	Sataro Goto Chiba, Japan	Video not available
11:20	Kim Janda La Jolla, USA	Immunopharmacotherapy against weight gain
11:50	Paola Scaffidi Bethesda, USA	Nuclear architecture: building bulwarks against aging
12:20	Pedro Alvarez Houston, USA	Video not available
12:50	Lunch
Session 6: short talks selected from submitted abstracts (Chairs: Giuseppina Colonna-Romano and Vadim Fraifeld)
13:50	Giuseppina Colonna-Romano Palermo, Italy	B cell immunosenescence in the elderly
14:05	Christian Dumpitak Duesseldorf, Germany	Accelerated protein aggregation and amyloid fibril formation of the prion protein in the presence of glycogen
14:20	John Schloendorn Tempe, USA	Video not available
14:35	Anund Hallen Uppsala, Sweden	Accumulating insoluble protein and rate of aging
14:50	Andrew Hessel Edmonton, Canada	Synthetic viruses targeting cancer
15:05	Vadim Fraifeld Beer-Sheva, Israel	Do mitochondrial DNA and metabolic rate complement each other in determination of the mammalian maximal life span?
15:20	Coffee
Session 7: New directions in gene therapy (Chair: Marisol Corral-Debrinski)
15:40	Nicola Philpott London, UK	Non-integrating lentiviral vectors for stable and efficient gene delivery to post-mitotic tissue
16:10	Michele Calos Palo Alto, USA	Adding beneficial genes to the body with phage integrases
16:40	Michael Holmes Richmond, USA	High efficiency human genome editing using designed zinc finger nucleases
17:10	Coffee
Session 8: Rescue of mitochondrial mutations (Chair: Michele Calos)
17:30	Volkmar Weissig Boston, USA	Manipulating (rejuvenating?) the mitochondrial genome
18:00	Dimitra Kyriakouli Newcastle upon Tyne, UK	Mutations of the mitochondrial genome: treatment
18:15	Mark Hamalainen for Ian Holt Cambridge, UK	Allotopic expression: mitochondrial to nuclear gene transfer
18:45	Marisol Corral-Debrinski Paris, France	Allotopic mRNA localization to the mitochondrial surface: a tool for rescuing respiration deficiencies
19:15	Tonio Enriquez Zaragoza, Spain	Inteins and allotopic expression of mtDNA encoded proteins
19:30	Samit Adhya Calcutta, India	Use of a parasite-derived protein complex to modulate the function of mitochondria in human cells
20:00	Dinner
21:00	Poster session 2
Saturday 8th September
7:30	Breakfast
Session 9: New approaches to eliminating beta-amyloid (Chair: Jan Vijg)
8:30	Ashley Bush Cambridge, USA	Zinc, copper and amyloid in Alzheimer's disease
9:00	Beka Solomon Tel Aviv, Israel	Immunological approaches for amyloid beta clearance toward Alzheimer's disease treatment
9:30	Yoh Matsumoto Tokyo, Japan	Non-viral Abeta DNA vaccine therapy against Alzheimer disease - safety, long-term effects and mechanisms of Abeta reduction
10:00	David Morgan Tampa, USA	Gene therapy with amyloid degrading proteases in mouse models of amyloid deposition
10:30	Coffee
Session 10: Non-specific nuclear DNA damage in aging (Chair: David Morgan)
10:50	Jan Vijg Novato, USA	Age-related stochastic dysfunction of the genome: a natural limit to life span?
11:20	Michael Siciliano Houston, USA	Microsatellite instability increases with age in normal individuals as well in patients with inherited mismatch repair mutations
11:50	Aubrey de Grey Cambridge, UK	Might the biogerontological impact of non-specific nDNA damage be slight?
12:20	Lunch
SENS Lecture (Chair: Aubrey de Grey)
13:20	Chris Phoenix Brooklyn, USA	Getting ahead of aging
Session 11: short talks selected from submitted abstracts (Chair: Aubrey de Grey)
14:05	Natasha Vita-More Austin, USA	Brave biological design -- how biotechnology, generative media, and other currents are changing creative inquiry in the arts & sciences
14:20	Anders Sandberg Oxford, UK	When Nature isn't wise: evolutionary medicine and human enhancement
14:35	Steven Horrobin Edinburgh, UK	The value of life to persons as conative processes
14:50	Coffee
Session 12: Engineering regeneration of complex structures (Chair: Miodrag Stojkovic)
15:10	David Steenblock Mission Viejo, USA	Bone marrow stem cell therapy: a major breakthrough for chronic diseases and anti-aging
15:25	James Larrick Mountain View, USA	Specific targeting of therapeutic stem cells for cardiovascular disease
15:40	Alexandra Stolzing for Amit Patel Leipzig, Germany	Cell fusion
16:10	Stephen Minger London, UK	Therapeutic applications of human stem cells - prospects and challenges
16:40	Chris Mason London, UK	Regenerative Medicine 2.0
17:10	David Gardiner Irvine, USA	Engineering a blastema: steps toward regenerating a limb
17:40	Coffee
Session 13: Deriving autologous embryonic stem cells (Chair: Chris Mason)
18:00	Chang-Kyu Lee Seoul, Korea	Interspecies somatic cell nuclear transfer for establishing embryonic stem cells with desired genotype
18:30	Wolfgang Engel Gottingen, Germany	Talk not given
19:00	Miodrag Stojkovic Valencia, Spain	Timeless human embryonic stem cells
19:30	Marius Wernig (Jaenisch lab) Cambridge, USA	Direct reprogramming of somatic cells into pluripotent stem cells
20:00	Dinner
21:00	Poster session 3
Sunday 9th September
7:30	Breakfast
Session 14: Telomeres and cell senescence (Chair: Mike Conboy)
8:30	Mary Perry Frederick, USA	The p53 inhibitory protein Mdm2 does not prevent aging
9:00	Gillian Butler-Browne Paris, France	Identification of biomarkers of human muscle aging and senescence
9:30	Lenhard Rudolph Hannover, Germany	Telomere dysfunction induces cell intrinsic checkpoints and environmental alterations limiting stem cell function
10:00	Walter Berger Wien, Austria	ALTernative ways to immortality. blessing or curse?
10:30	Coffee
Session 15: Maintenance of extracellular material and milieu (Chair: Gillian Butler-Browne)
10:50	Robin Franklin for Julia Rist Cambridge, UK	Ageing and myelin repair in the CNS
11:20	Mike Conboy Berkeley, USA	Stem cells dividing, sister chromatids choose fate: old stays, young moves on
11:50	Cato Laurencin Charlottesville, USA	Video not available
12:20	Lunch
Session 16: short talks selected from submitted abstracts (Chairs: Matthew O'Connor and David Melzer)
13:20	Calogero Caruso Palermo, Italy	Genetics of successful ageing: goals and future perspectives, a pharmacogenomics approach to prevent unsuccessful ageing
13:35	David Melzer Exeter, UK	Genetic polymorphisms and human ageing: lessons for SENS
13:50	Andrew Mayes Sharnbrook, UK	Repetitive mild heat shock as a mechanism to delay ageing in human dermal fibroblasts
14:05	Eugenio Mocchegiani Ancona, Italy	Zinc, metallothioneins and longevity: effect of zinc supplementation. ZINCAGE study
14:20	Dawn Mazzatti Sharnbrook, UK	Age-dependent effects of zinc on gene expression and zinc status in peripheral blood mononuclear cells
14:35	Alexander Michalow Bourbonnais, USA	Searching for the fountain of youth: novel caloric restriction mimetics
14:50	Oren Froy Rehovot, Israel	The relationship between calorie restriction and the biological clock: lessons from long-lived transgenic mice
15:05	Mikhail Shchepinov Oxford, UK	Isotope effect and enhanced longevity
15:20	Sergiy Volovyk Durham, USA	Talk not given
15:35	Matthew O'Connor Berkeley, USA	Stem cells endogenous to aged skeletal muscle retain high telomerase activity
15:50	Coffee
Session 17: Long-term goals for biomedical gerontology (Chair: Michael Rose)
16:10	Ben Best Detroit, USA	Evidence that cryonics may work
16:40	Ray Kurzweil Boston, USA	Accelerating change
17:40	Coffee
Session 18: Outreach to key stakeholder communities (Chair: Aubrey de Grey)
18:00	Linda Powers Bethesda, USA	Pots of gold in anti-aging regenerative medicine?
18:30	Michael Rose Irvine, USA	Slowing and then stopping aging
19:00	Huber Warner Minneapolis, USA	Making the political case for biogerontology funding: a view from the trenches
19:30	Bernard Siegel Wellington, USA	The inevitable legal battle over Engineered Negligible Senescence

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