| SENS Besprechungen |
| Besprechungen |
1 |
2 |
3 |
4 |
| Konferenzen |
1 |
2 |
|
|
Aubrey de Greys Publikationen
Die meisten der folgenden Publikationen werden als
PDFs von Vorabversionen bereitgestellt. Wo das nicht möglich ist gibt es
Links zu den Abstracts. Sie können auch Nachdrucke bestellen.
Einführungen für
den Laien
Überblick über
die Wissenschaft, auf der SENS basiert
Soziale Aspekte
von SENS, auch innerhalb der Biogerontologie
Unschädlich machen
mitochondrialer Mutationen
Entfernen
lysosomaler Aggregate
Ein ultimatives
Krebsheilmittel
Mitochondriale
Mutationen und ihre Auswirkungen
Andere
Einführung für den Laien
:
de Grey ADNJ. An engineer's approach to the
development of real anti-aging medicine. Science's
SAGE KE 2003; 2003(1):vp1. Also in: The Fountain of Youth: Ethical,
Religious, and Existential Perspectives on a Biomedical Goal (S.G. Post,
ed.), Oxford University Press, 2003, pp. 249-267. PDF
de Grey
ADNJ. Escape velocity: why the prospect of extreme human life extension
matters now. PLoS
Biol 2004; 2(6):723-726. PDF
Die meisten
meiner Publikationen sind für spezialisierte Biogerontologen geschrieben.
Die obingen sind jedoch auch für eine allgemeinere Leserschaft
verständlich. Wenn Sie neu auf diesem Gebiet sind, oder wenn Sie kein
Biologe sind, fangen sie mit denen an.
Überblick über die Wissenschaft, auf der SENS
basiert:
de Grey ADNJ, Ames BN, Anderson JK, Bartke A, Campisi J,
Heward CB, McCarter RJM, Stock G. Time to talk SENS: critiquing the
immutability of human aging. In: Increasing Healthy Life Span:
Conventional Measures and Slowing the Innate Aging Process - Ninth
Congress of the International Association of Biomedical Gerontology (D.
Harman, ed.), Annals
NY Acad Sci 2002; 959:452-462. PDF
de Grey
ADNJ. An engineer's approach to the development of real anti-aging
medicine. Science's SAGE KE 2003; http://sageke.sciencemag.org/cgi/content/full/sageke;2003/1/vp1
Also in: The Fountain of Youth: Ethical, Religious, and Existential
Perspectives on a Biomedical Goal (S.G. Post, ed.), Oxford University
Press, 2004, pp. 249-267. PDF
de Grey
ADNJ. Challenging but essential targets for genuine anti-ageing drugs. Expert
Opinion on Therapeutic Targets 2003; 37(1):1-5. PDF
de Grey
ADNJ. UK research on the biology of aging -- the next ten years. Lifespan
2003; 11(1):1-4. PDF
Soziologische Aspekte von SENS, auch innerhalb der
Biogerontologie:
de Grey ADNJ. Gerontologists and the media: the
dangers of over-pessimism. Biogerontology
2000;1(4):369-370. PDF
de Grey
ADNJ, Gavrilov L, Olshansky SJ, Coles LS, Cutler RG, Fossel M, Harman SM.
Antiaging technology and pseudoscience. Science
2002; 296(5568):656. PDF
de Grey
ADNJ, Baynes JW, Berd D, Heward CB, Pawelec G, Stock G. Is human aging
still mysterious enough to be left only to scientists? BioEssays
2002; 24(7):667-676. PDF
de Grey
ADNJ. Fear of misrepresentation cannot justify silence about foreseeable
life-extension biotechnology. BioEssays
2003; 25(1):94-95. PDF
de Grey
ADNJ. The foreseeability of real anti-aging medicine: focusing the debate.
Exp
Gerontol 2003; 38(9):927-934. PDF
de Grey
ADNJ. Biogerontologists' duty to discuss timescales publicly. Annals NY Acad
Sci 2004; 1019:542-545. PDF
de Grey ADNJ.
Escape velocity: why the prospect of extreme human life extension matters
now. PLoS
Biol 2004; 2(6):723-726. PDF
de Grey ADNJ.
The war on aging. In: The
Scientific Conquest of Death (B.J. Klein et al., eds.), Libros en Red,
2004, pp. 17-29. PDF
de Grey
ADNJ. Leon Kass: quite substantially right. Rejuvenation
Res 2004; 7(2):89-91. PDF
de Grey
ADNJ. Three self-evident life-extension truths. Rejuvenation
Res 2004; 7(3):165-167. PDF
de Grey
ADNJ. Aging, childlessness or overpopulation: the future's right to
choose. Rejuvenation Res 2004; 7(4):237-238. PDF
Unschädlich machen mitochondiraler Mutationen:
de Grey ADNJ. Are those 13 proteins really
unimportable? In: From Symbiosis to Eukaryotism - Endocytobiology VII (E.
Wagner et al., eds.), Geneva University Press, 1999, pp.
489-502.
de Grey ADNJ. Mitochondrial gene therapy: an arena for the
biomedical use of inteins. Trends
Biotechnol 2000; 18(9):394-399. PDF
de Grey ADNJ.
Response to "approaches and limitations to gene therapy for mitochondrial
diseases," Antioxid. Redox Signal. 2001;3:451-460. Antioxid
Redox Signal 2001; 3(6):1153-1155. PDF
de Grey
ADNJ. Inter-species therapeutic cloning: the looming problem of
mitochondrial DNA and two possible solutions. Rejuvenation
Res 2004; 7(2): 95.98. PDF
Entfernen lysosomaler Aggregate:
de
Grey ADNJ. Bioremediation meets biomedicine: therapeutic translation of
microbial catabolism to the lysosome. Trends
Biotechnol 2002; 20(11): 452-455. PDF
Ein totales Krebsheilmitel:
de Grey ADNJ,
Campbell FC, Dokal I, Fairbairn LJ, Graham GJ, Jahoda CAB, Porter ACG.
Total deletion of in vivo telomere elongation capacity: an ambitious but
possibly ultimate cure for all age-related human cancers. Annals NY Acad
Sci 2004; 1019:147-170. PDF
Mitochondriale Mutationen und ihre Auswirkungen:
de Grey ADNJ. A proposed refinement of the
mitochondrial free radical theory of aging. BioEssays
1997; 19(2):161-166. PDF
de Grey ADNJ.
A mechanism proposed to explain the rise in oxidative stress during aging.
J Anti-Aging Med 1998; 1(1):53-66. PDF
de Grey ADNJ.
The
mitochondrial free radical theory of aging. Austin, TX: Landes
Bioscience, 1999, 212pp, hardcover (ISBN 1-57059-564-X).
de Grey
ADNJ. The non-correlation between maximum longevity and enzymatic
antioxidant levels among homeotherms; implications for retarding human
aging. J Anti-Aging Med 2000; 3(1):25-36. PDF
de Grey ADNJ.
The reductive hotspot hypothesis: an update. Arch
Biochem Biophys 2000; 373(1):295-301. PDF
de Grey ADNJ.
The reductive hotspot hypothesis of mammalian aging: membrane metabolism
magnifies mutant mitochondrial mischief. Eur
J Biochem 2002; 269(8):2003-2009. PDF
de Grey
ADNJ. Mitochondrial mutations in vertebrate aging. In: Oxidative stress
and aging: advances in basic science, diagnostics, and intervention
(R.G. Cutler and H. Rodriguez, eds.), World Scientific Publishing, 2002,
pp. 437-451. PDF
de Grey
ADNJ. Mechanisms underlying the age-related accumulation of mutant
mitochondrial DNA. In: Genetics of mitochondrial diseases (I.J. Holt,
ed.), Oxford University Press, 2003, pp. 247-275. PDF
de Grey
ADNJ. Mitochondria in homeotherm aging: will detailed mechanisms
consistent with the evidence now receive attention? Aging
Cell 2004; 3(2):77. PDF
de Grey
ADNJ. Mitochondrial mutations in mammalian aging: an over-hasty
about-turn? Rejuvenation
Res 2004; 7(3): 171-174. PDF
Andere:
de Grey ADNJ. Incorporation of
transmembrane hydroxide transport into the chemiosmotic theory. Bioelectrochem
Bioenerg 1999; 49(1-2):43-50. PDF
de Grey
ADNJ. Biologists abandon Popper at their peril. BioEssays
2000; 22(2):206-207. PDF
de Grey
ADNJ. A proposed mechanism for the lowering of mitochondrial electron leak
by caloric restriction. Mitochondrion
2001; 1(2):129-139. PDF
de Grey
ADNJ. UK research on the biology of aging. Exp
Gerontol 2001; 37(1):1-7. PDF
de Grey
ADNJ. Response to "telomere shortening with aging in human liver". J
Gerontol A Biol Sci Med Sci 2001; 56(6):B237-B238. PDF
de Grey
ADNJ. HO2: the forgotten radical. DNA
Cell Biol 2002; 21(4):251-257. PDF
de Grey
ADNJ. Critique of the demographic evidence for "late-life non-senescence".
Biochem
Soc Trans 2003; 31(2):452-454. PDF
de Grey
ADNJ. A proposal for the overall structure of the mammalian plasma
membrane redox system. Protoplasma
2003; 221(1-2):3-9. PDF
de Grey
ADNJ. Overzealous maximum-likelihood fitting falsely convicts the slope
heterogeneity hypothesis. Exp
Gerontol 2003; 38(8):921-923. PDF
de Grey
ADNJ. Falsifying falsifications: the most critical task of theoreticians
in biology. Medical
Hypotheses 2004; 62(6):1012-1020. PDF
de Grey
ADNJ. The unfortunate influence of the weather on the rate of aging: why
human caloric restriction or its emulation may only extend life expectancy
by 2-3 years. Gerontology 2005, in press. PDF
|