Our next intern Connie Wang explains her part in uncovering the complex links between microglia cells and Alzheimer's disease.
Intern Sam Curran: IDing Senescent Cell Secretion Potentially Implicated In Age-Related Decline Of Immune System FunctionPosted by Iain Inkster on June 26, 2013 | SRF Education
In our previous Intern Spotlight we learned about harmful proteins secreted from senescent cells that promote tumor growth in surrounding tissue. Senescent cells also contribute to other pathologies associated with old age, such as tissue degeneration. Is there a way to target and treat the afflicted cells responsible here too? This is the question being addressed by our next intern, Sam Curran.
Our next Intern Spotlight reveals how Nick Schaum is working with the Buck Institute to make chemotherapeutic drugs more effective, with one method already in clinical trials.
SRF Education has a new director, who will be working with student researchers. What does he think about his new role?
Ever wondered what it’s like to intern with SENS Research Foundation? SRF Education is proud to present the first in a series of Intern Spotlights. Read more to find out how Ali Crampton devised a method to ensure the reliability of research into damaged mitochondrial genes at SRF’s laboratories here in Mountain View, CA.
SRF Education has chosen thirteen students to intern at six different institutions this summer. Our world-leading extramural host institutions include the Wake Forest Institute for Regenerative Medicine, the University of Cambridge, the Buck Institute for Research on Aging, the State University of New York Upstate Medical University, and the Weizmann Institute of Science.
With the launch of SENS Research Foundation's new website, the SENS Foundation Academic Initiative is now SRF Education. We hope that this new name will further clarify our mission and role within the larger Foundation. SRF Education's purpose continues to be centered on students and laypeople who are interested in learning more about SENS.
The SENS Foundation Academic Initiative has not exhausted the funding that it has allocated towards grants for the year 2012.
A literature review written by members of SRF Education has been published in Rejuvenation Research, and is now posted on PubMed.
The Academic Initiative's single largest project is the open online course that we are developing. We have determined the format that our videos in this course will take: they will display the image of a slide on-screen when that slide is most relevant. This way, every viewer will be able to see the right slides at the right time, instead of having to figure out precisely which slide the lecturer is discussing on their own.
In early March, the microglia project started when the Academic Inititiative awarded me a small grant to begin setting up functional assays for microglia. I've attached that grant and listed the background information section, without citations, below.
Microglia make up about 5-12% of total brain cells and act as the main immune cells of the CNS, but their function becomes increasingly impaired with age. In July two of the summer interns, Connie Wang and Jennie Sims, submitted a grant proposal that would continue to develop a project to assess exactly what changes occur in aging microglia.