My name is Christine Wu, and I am a rising senior studying at the University of Pennsylvania who is working to achieve a Biological Basis of Behavior degree and a Creative Writing minor. At the SENS Research Foundation, I work in the OncoSENS department with Dr. Haroldo Silva. My project will study a specific pathway used by cancer cells called the Alternative Lengthening of Telomeres (ALT) pathway with the use of the ALT-associated promyelocytic leukemia (PML) nuclear bodies (APB) assay. The results generated by the APB assay will provide new data to better assess the potential of drugs for cancer therapy, particularly for tumors associated with the ALT mechanism.
Research Update by Julie Marco: Fibrin Provides Necessary Structural Integrity to Thymus Tissue ScaffoldsPosted by Greg Chin on June 05, 2014 | SRF Education
Research Update by Julie Marco: Fibrin Provides Necessary Structural Integrity to Thymus Tissue Scaffolds
Undergraduate Research Profile: Evaluation of Cell Therapies for Intestinal Bowel Disease by Connor Crowley (WFIRM)Posted by Iain Inkster on March 10, 2014 | SRF Education
Hello, my name is Connor Crowley, and I am a junior studying biochemistry at Wake Forest University. I have always been extremely interested in the incredible possibilities of regenerative medicine and was thrilled to hear that I was selected as a SRF-WFIRM research scholar. While I don’t believe that I have a specific moment in time that definitively pushed me towards regenerative medicine, I do believe that we have all seen the devastating effects that aging can have on our loved-ones, friends, and family members. Throughout my short 20-year life I have watched my grandfather’s life transform, all due to the effects of aging. When I was younger, he always played golf and baseball beside me.
My name is Julie Marco, and I am a junior at Wake Forest University. I am working toward a Bachelor of Science in chemistry with a concentration in biochemistry and a biology minor. I initially became involved with research while in high school under the dual-mentorship of Dr. Michael Tsang (Department of Biochemistry and Molecular Genetics) and Dr. Beth Roman, (Department of Biology) at the University of Pittsburgh. My high school research project utilized zebrafish as a model for determining if age played a role in how they regenerated fin and cardiac tissues. The results demonstrated a positive correlation between age and regeneration and also identified genes that are needed at different stages of cardiac tissue regeneration. My early research experience investigating how age affects regeneration is what sparked my interest in the SENS Research Foundation (SRF). I wanted to be able to learn and see new techniques that are being used to try to help slow down or reverse the process of aging.
SENS Research Foundation is proud to announce a new partnership with the Wake Forest Institute for Regenerative Medicine (WFIRM) to provide undergraduate students in the Winston-Salem area the opportunity to join physicians and scientists at WFIRM in translating scientific discovery into clinical therapies. Wake Forest University undergraduates Julie Marco and Connor Crowley, who were selected by Dr. John Jackson and Dr. Graca Almeida-Porada respectively, are the first students to join the SRF Undergraduate Research Program. In the coming undergraduate research profiles, you will learn more about each new research scholar as well as Julie’s new thymus tissue regeneration project in the Jackson lab and Connor’s project evaluating cell therapies for inflammatory bowel disease (IBD) in the Almeida-Porada lab.
Stem cell-based therapy for the treatment of inflammatory bowel disease (IBD) – SRF intern John MoonPosted by Iain Inkster on February 13, 2014 | SRF Education
John is currently a senior at Vassar College majoring in Biology. Since 2011, he has been studying the neuroprotective effects of hormones released following traumatic brain injury in the laboratory of Dr. Kelli A. Duncan. During his 2013 SENS Research Foundation (SRF) Summer Internship Program, he joined the laboratory of Dr. Graca Almeida-Porada at the Wake Forest Institute for Regenerative Medicine and helped develop a stem-cell based therapy for the treatment of inflammatory bowel disease (IBD) in mouse models.
Daniel is currently pursuing a degree in biology with a focus on neurobiology at North Carolina State University (NCSU). However, Daniel’s journey to the 2013 SRF Summer Internship Program is quite unique. He began his research career in 2004 exploring the genomic basis of fungal resistance in melons with Dr. Tarek Joober at NCSU. While pursuing a degree in psychology at the University of North Carolina-Chapel Hill (UNC), Daniel used EEG, fMRI and eye-tracking paradigms to study the effects of memory on attentional control under the supervision of Dr. Joseph Hopfinger. After studying cognitive science for two years at the University of Cincinnati, Daniel decided a “bottom-up” approach was more amenable to his research interests and enrolled at NCSU where he is currently attempting to develop a zebrafish model of trait-level anxiety under the mentorship of Dr. John Godwin. ..
Anuj is pursuing a B.S. in Biomedical Engineering at the University of Texas in Austin, where he has been involved with numerous student organizations and undergraduate research projects, including a study of early T-cell differentiation from blood-forming cells as well as a project studying the differentiation of fat-derived stem cells into different layers of cartilage...
Evidence that Cell Senescence is a Factor in Chronic Obstructive Pulmonary Disease -- SRF intern Shahar BrachaPosted by Iain Inkster on January 14, 2014 | SRF Education
Shahar began taking classes at Tel Aviv University when she was only 15 years old. At age 16, she independently completed her matriculation exams to become a full-time student at Tel Aviv University, and, in the process, became youngest student ever to enroll at the faculty. In 2013, she was awarded a Bachelor of Science Degree in Biology.
A Study of the Effect of Histone Acetylation on ATM Activation and the SASP by SRF Intern Meredith GiblinPosted by Iain Inkster on December 04, 2013 | SRF Education
Meredith Giblin is a senior at Rensselaer Polytechnic Institute (RPI) in Troy, NY, where she is majoring in Biochemistry and Biophysics. During her first three years at RPI, Meredith worked in the laboratories of Dr. Robert Linhardt and Dr. Patrick Maxwell.....
Investigating the Mechanism of Lithium Treatment of a Parkinson’s Disease Model with SRF Intern Sean BatirPosted by Iain Inkster on November 22, 2013 | SRF Education
Sean is a senior at the Massachusetts Institute of Technology (MIT), where he is studying computer science and biology. His long-standing interest in neurology led him to MIT’s Synthetic Neurobiology Group, led by Dr. Edward Boyden...
Eric received his B.S. in Biology from Maryville University in St. Louis in May 2013. There, under the tutelage of Dr. Gabriel Colbeck, Eric studied Black-capped and Carolina Chickadees. He tried to determine the ratio between black-capped, Carolina, and back-capped/Carolina hybrids, assess the impact of bird song on reproductive success amongst these groups...