My name is Shruti Singh, and I am a rising senior at the University of Texas at Austin. I am majoring in Human Biology with a concentration in immunity and pathogenesis.This summer, I am working on a thymus regeneration project in Dr. John Jackson’s lab at the Wake Forest Institute for Regenerative Medicine.
My name is Ethan Bassin, and I am a rising senior majoring in Bioengineering at the University of Pennsylvania. This summer, as a SENS Research Foundation (SRF) Summer Scholar at WFIRM, I am working on a whole kidney engineering project under the mentorship of Dr. James Yoo and Dr. Anthony Atala.
My name is Haben Tesfamariam, and I recently graduated from the University of Texas at Austin with a B.S. in Cell and Molecular Biology. This summer I will be working with Dr. Mark McCormick in the laboratory of Dr. Brian Kennedy at the Buck Institute for Research on Aging. I will be testing the role of recently uncovered translation-related genes in lifespan extension and determining whether any lifespan increase is dependent upon the nutrient responsive transcription factor Gcn4.
My name is Megan Harper. I am a junior double majoring in neuroscience and computer science at the University of Virginia. My project with the Campisi lab at the Buck Institute for Research on Aging will address the following questions: 1) Which chemotherapy drug or irradiation dose currently used for treatment of cancer patients induces senescence in the tissue microenvironment? 2) How does the phenotype of senescent cells respond to HIF-1a regulation and to different oxygen concentrations?
My name is Joi McLaughlin. I am a recent graduate of Duke University where I received a Bachelor’s of Art degree in Visual Arts with a Minor in Chemistry while pursuing a Pre-Medical School Curriculum. This summer, at the Buck Institute For Research on Aging, I will be working on a project in the laboratory of Dr. Heinrich Jasper examining the effect of unfolded proteins in fruit fly mitochondria on stem cell maintenance.
SENS Research Foundation is pleased to announce the start of the 2014 SRF Summer Scholars Program. This year, fifteen SRF summer scholars will be hosted by the Buck Institute for Research on Aging, the Harvard Stem Cell Institute / Harvard Medical School, University College London, the University of Oxford, the Wake Forest Institute for Regenerative Medicine, and our very own SRF Research Center.
My name is Christine Wu, and I am a rising senior studying at the University of Pennsylvania who is working to achieve a Biological Basis of Behavior degree and a Creative Writing minor. At the SENS Research Foundation, I work in the OncoSENS department with Dr. Haroldo Silva. My project will study a specific pathway used by cancer cells called the Alternative Lengthening of Telomeres (ALT) pathway with the use of the ALT-associated promyelocytic leukemia (PML) nuclear bodies (APB) assay. The results generated by the APB assay will provide new data to better assess the potential of drugs for cancer therapy, particularly for tumors associated with the ALT mechanism.
Research Update by Julie Marco: Fibrin Provides Necessary Structural Integrity to Thymus Tissue ScaffoldsPosted by Greg Chin on June 05, 2014 | SRF Education
Research Update by Julie Marco: Fibrin Provides Necessary Structural Integrity to Thymus Tissue Scaffolds
Undergraduate Research Profile: Evaluation of Cell Therapies for Intestinal Bowel Disease by Connor Crowley (WFIRM)Posted by Iain Inkster on March 10, 2014 | SRF Education
Hello, my name is Connor Crowley, and I am a junior studying biochemistry at Wake Forest University. I have always been extremely interested in the incredible possibilities of regenerative medicine and was thrilled to hear that I was selected as a SRF-WFIRM research scholar. While I don’t believe that I have a specific moment in time that definitively pushed me towards regenerative medicine, I do believe that we have all seen the devastating effects that aging can have on our loved-ones, friends, and family members. Throughout my short 20-year life I have watched my grandfather’s life transform, all due to the effects of aging. When I was younger, he always played golf and baseball beside me.
My name is Julie Marco, and I am a junior at Wake Forest University. I am working toward a Bachelor of Science in chemistry with a concentration in biochemistry and a biology minor. I initially became involved with research while in high school under the dual-mentorship of Dr. Michael Tsang (Department of Biochemistry and Molecular Genetics) and Dr. Beth Roman, (Department of Biology) at the University of Pittsburgh. My high school research project utilized zebrafish as a model for determining if age played a role in how they regenerated fin and cardiac tissues. The results demonstrated a positive correlation between age and regeneration and also identified genes that are needed at different stages of cardiac tissue regeneration. My early research experience investigating how age affects regeneration is what sparked my interest in the SENS Research Foundation (SRF). I wanted to be able to learn and see new techniques that are being used to try to help slow down or reverse the process of aging.
SENS Research Foundation is proud to announce a new partnership with the Wake Forest Institute for Regenerative Medicine (WFIRM) to provide undergraduate students in the Winston-Salem area the opportunity to join physicians and scientists at WFIRM in translating scientific discovery into clinical therapies. Wake Forest University undergraduates Julie Marco and Connor Crowley, who were selected by Dr. John Jackson and Dr. Graca Almeida-Porada respectively, are the first students to join the SRF Undergraduate Research Program. In the coming undergraduate research profiles, you will learn more about each new research scholar as well as Julie’s new thymus tissue regeneration project in the Jackson lab and Connor’s project evaluating cell therapies for inflammatory bowel disease (IBD) in the Almeida-Porada lab.
Stem cell-based therapy for the treatment of inflammatory bowel disease (IBD) – SRF intern John MoonPosted by Iain Inkster on February 13, 2014 | SRF Education
John is currently a senior at Vassar College majoring in Biology. Since 2011, he has been studying the neuroprotective effects of hormones released following traumatic brain injury in the laboratory of Dr. Kelli A. Duncan. During his 2013 SENS Research Foundation (SRF) Summer Internship Program, he joined the laboratory of Dr. Graca Almeida-Porada at the Wake Forest Institute for Regenerative Medicine and helped develop a stem-cell based therapy for the treatment of inflammatory bowel disease (IBD) in mouse models.