Program
While this provisional schedule is still subject to change, it is expected to be generally accurate.
| Wednesday 31st August | ||
| 11:30 | Registration opens | |
| 12:30 | Lunch | |
| Session 1 New advances in tissue engineering | ||
| 13:30 | Suwan Jayasinghe University College London, UK |
Biospray techniques for engineering organotypic tissues |
| 14:00 | Shay Soker Wake Forest Institute of Regenerative Medicine, USA |
Tissue engineering of the liver using decellularised scaffolds |
| 14:30 | Laura Niklason Yale University, USA |
Lung Regeneration: Progress and Challenges |
| 15:00 | John Jackson Wake Forest Institute of Regenerative Medicine, USA |
Thymic Tissue Regeneration Using Natural Scaffolds |
| 15:30 | Coffee | |
| Session 2 New advances in stem cells | ||
| 16:00 | Xiao-Dong Chen U. Texas Health Sciences Center, USA |
Rescuing Aged Mesenchymal Stem Cells by Exposure to a Young Extracellular Matrix |
| 16:30 | Mariusz Ratajczak University of Louisville, USA |
Very Small Embryonic Like Stem Cells (VSELs) – our key to longevity and passkey to cancer? |
| 17:00 | Dan Kaufman University of Minnesota, USA |
Differentiation of iPS cells into NK cells to combat cancer and HIV |
| 17:30 | Minoru Ko National Institutes of Health, USA |
What can we learn about immortality from embryonic stem cells? |
| 18:00 | Coffee | |
| Session 3 Cancer | ||
| 18:15 | Mike Berridge Malaghan Institute of Medical Research, New Zealand |
Mitochondrial gene transfer to transplantable tumours lacking a mitochondrial genome |
| 18:30 | Bill Andrews Sierra Sciences, USA |
Small-molecule stimulators of telomerase |
| 19:00 | Michael Lisanti Thomas Jefferson University, USA |
Parasitic metabolic coupling in cancer: Understanding oxidative stress and autophagy in the tumor microenvironment |
| 19:30 | Dipnarine Maharaj South Florida Bone Marrow Stem Cell Transplant Institute, USA |
Leucocyte transfusions as a novel immunotherapy for cancer patients |
| 20:00 | Dinner | |
| 21:00 | Poster Session | |
| Thursday 1st September | ||
| 07:30 | Breakfast | |
| Session 4 Mesenchymal and visceral rejuvenation | ||
| 08:30 | Nathan LeBrasseur Mayo Clinic, USA |
Myostatin: Modulator of Muscle Mass, Mobility and Metabolism |
| 09:00 | Graca Almeida-Porada Wake Forest Institute of Regenerative Medicine, USA |
Cellular Therapy for Intestinal Regeneration |
| 09:30 | James Kirkland Mayo Clinic, USA |
Aging, Adipose Tissue, and Cellular Senescence |
| 10:00 | Coffee | |
| Session 5 Brain aging: 1 | ||
| 10:15 | David Rubinsztein University of Cambridge, UK |
Autophagy, a guardian against neurodegeneration |
| 10:45 | Einar Sigurdsson New York University, USA |
Clearance of Pathological Tau Protein with Immunotherapy |
| 11:15 | Ben Bahr University of North Carolina Pembroke, USA |
Positive Lysosomal Modulation to Treat Age-Related Protein Accumulation Diseases |
| 11:45 | Matthew Wood Oxford University, UK |
Trans-BBB exosomes |
| 12:15 | Beverly Steffert Brainmaster Technologies Inc. |
Neuroplasticity and Connectivity in the Aging Brain |
| 12:30 | Lunch | |
| Session 6 Short talks | ||
| 14:00 | Daniel Kimbel SENS Foundation |
The Future of SENSFAI |
| 14:15 | Kristen Fortney University of Toronto, Canada |
Computationally mining genome-wide drug-response compendia to discover novel calorie restriction mimetics |
| 14:30 | Erika Taidre Tallinn University of Technology, Estonia |
Last Economic Recession Was Good for Life Expectancy |
| 14:45 | Jonathan Heddle RIKEN, Japan |
How Can CR Inform Therapeutic Strategies? |
| 15:00 | Lucas Trindade RIKEN, Japan |
Aging Theories: a new perspective |
| 15:15 | Kent Kemmish Halcyon Molecular, USA |
Improved Sequencing as a SENS Accelerant |
| 15:30 | Bernd-Michael Loeffler Institute for Preventive and Aesthetic Medicine, Germany |
Intervall-Hypoxia-Hyperoia-Therapy as a non-invasive tool to treat chronic diseases based on mitochondrial dysfunction |
| 15:45 | Giorgio Aicardi University of Bologna, Italy |
Impairments in synaptic plasticity in aged animals and in animal models of Alzheimer's disease |
| 16:00 | Peter Fedichev Quantum Pharmaceuticals |
De-novo geroprotector design |
| 16:15 | Coffee | |
| Session 7 Brain aging: 2 | ||
| 16:30 | Charles Greer Yale University, USA |
Aging of Synaptic Circuits |
| 17:00 | Rodolfo Goya Universidad Nacional de La Plata, Argentina |
Gene therapy and nanotechnology as interventive strategies for the aging brain |
| 17:30 | Jean Hébert Albert Einstein College of Medicine, USA |
Neuron replacement in the neocortex |
| 18:00 | Susanne Funke ICS-6, Forschungszentrum Juelich, Germany |
An amyloid-β binding peptide modulates Aβ oligomerization and is a possible candidate for therapy of Alzheimer’s disease |
| 18:15 | Coffee | |
| Session 8 Nuclear and mitochondrial mutations and epimutations in aging | ||
| 18:30 | Silvia Gravina Albert Einstein College of Medicine, USA |
Epigenetic Drift and Aging |
| 19:00 | Matthew O'Connor SENS Foundation |
MitoSENS: Allotopic expression of mitochondrial genes using a co-translational import strategy |
| 19:30 | Michael Teitell University of California, Los Angeles, USA |
The impact of PNPASE on the therapeutic potential of mitochondrial RNA import |
| 20:00 | Dinner | |
| 21:00 | Poster Session | |
| Friday 2nd September | ||
| 07:30 | Breakfast | |
| Session 9 Novel antibody technology | ||
| 08:30 | Kenneth Shea U. California Irvine, USA |
Plastic Antibodies, Synthetic Receptors for Biological Macromolecules |
| 09:00 | Michael Sierks Arizona State University, USA |
Nanobodies against APP |
| 09:30 | Graziella El Khoury University of Cambridge, UK |
Camelid antibodies in medicine |
| 10:00 | Coffee | |
| Session 10 Novel treatments for cardiovascular disease | ||
| 10:15 | Jacques Mathieu Rice University, USA |
Lysosomal enhancement strategies for the treatment of oxysterol-induced cytotoxicity |
| 10:45 | Lorenzo Albanello SENS Foundation |
LysoSENS: a synthetic biology approach to treat age related macular degeneration |
| 11:00 | Alexandr Kharlamov Ural State Medical Academy, Russia |
Plasmonic Photothermal Therapy of Atherosclerotic Plaque with the Use of Silica-Gold Nanoparticles and Stem Cells versus Ferro-Magnetic Approach |
| 11:30 | Robert Shmookler-Reis University of Arkansas, USA |
Aspirin, the oldest new anti-aging drug |
| 12:00 | Lunch | |
| Session 11 SENS Lecture and short talks | ||
| 13:45 | Caleb Finch U. Southern California, USA |
SENS Lecture: The future of human lifespans, a demographic perspective |
| 14:45 | Sonia Arrison Pacific Research Institute, USA |
100 Plus: How the Coming Age of Longevity Will Change Everything, From Careers and Relationships to Family and Faith |
| 15:00 | Didier Coeurnelle Molenbeek, Brussels |
Longevity as a catalyst of non-violence |
| 15:15 | Bennett Foddy Institute for Science and Ethics, Oxford University |
Allocating resources for rejuvenation therapies |
| 15:30 | Vladimir Burdyuzha Lebedev Physical Inst., Russian Academy of Sciences (Moscow) |
International Scientific Center for Research of the Future |
| 15:45 | Alexey Moskalev Institute of Biology, Russian Academy of Sciences |
The effects of DNA damage response and repair genes overexpression on Drosophila melanogaster lifespan |
| 16:00 | James Larrick Panorama Research Institute, USA |
Trophokines: Novel therapies for Senescence |
| 16:15 | Coffee | |
| Session 12 Crosslink accumulation in the extracellular matrix | ||
| 16:30 | Daniel Nyhan Johns Hopkins Medical Institute, USA |
The Role of Transglutaminase-2 in Vascular Stiffness |
| 17:00 | Paul Thornalley University of Warwick, UK |
Increased damage to proteins in ageing – wear and tear potentially avoidable by extending preventive maintenance of life’s essential machinery |
| 17:30 | David Spiegel Yale University, USA |
Chemical Strategies for Exploring Advanced Glycation End-Products |
| 18:00 | Naila Rabbani University of Warwick, UK |
The pro-atherogenic phenotype in ageing – lipoprotein B100 and A1 leading the dance into decline of vascular health by oxidative and non-oxidative mechanisms |
| 18:15 | Coffee | |
| Session 13 Regeneration of non-vital organs | ||
| 18:30 | Chongxi Yu Techfields Pharma, China |
Large life extension in mice using transdermal delivery of an aspirin pro-drug |
| 19:00 | Paolo Macchiarini Karolinska Institutet, Sweden |
Trachea and oesophagus tissue engineering |
| 19:30 | James Yoo Wake Forest Institute of Regenerative Medicine, USA |
Creation of Functional Ovarian Tissue |
| 20:00 | Dinner | |
| 21:00 | Poster Session | |
| Saturday 3rd September | ||
| 07:30 | Breakfast | |
| Session 14 Bioinformatics in aging | ||
| 08:30 | Alex Zhavoronkov Biogerontology Research Foundation, UK |
AgingPortfolio.Org knowledge management system for aging research |
| 09:00 | John Furber Legendary Pharmaceuticals, USA |
A Guided Tour Down the Pathways of Aging |
| 09:15 | Pat Langley Arizona State University, USA |
Computational Support for Systems Biology of Aging |
| 09:45 | Maria Konovalenko Science for Life Extension Foundation, Russia |
Integrated system of aging biomarkers |
| 10:15 | Walter Arancio University of Palermo, Italy |
A Bioinformatics Analysis of Lamin A Regulatory Network: a Perspective on Epigenetic Involvement in Hutchinson-Gilford Progeria Syndrome |
| 10:30 | Coffee | |
| Session 15 Immunorejuvenation | ||
| 10:45 | Janko Nikolich-Zugich University of Arizona, USA |
Rebalancing the aging T-cell pool to improve resistance to infection in the old age |
| 11:15 | Doron Melamed Technion, Israel |
Rejuvenating the B-lymphocyte lineage in aging |
| 11:45 | Iryna Pishel State Institute of Gerontology, Ukrainian Academy of Medical Sciences |
Cells and niches transplantation as approaches to the immune system rejuvenation |
| 12:00 | Lunch | |
| Session 16 Short talks | ||
| 14:00 | Justin Rebo ImmunePath |
Embryonic Stem Cell Strategies for the Realization of Rejuvenation Biotechnology |
| 14:15 | Gregory Brewer Southern Illinois University School of Medicine, USA |
Aging brain mitochondrial dysfunction: metabolic rejuvenation |
| 14:30 | Caridad Fernández International Centre for Neurological Restoration, Cuba |
Cellular “functional replacement” with a “cell-free strategy” in early Alzheimer's and Parkinson's diseases: evidences from related animal models |
| 14:45 | Calogero Caruso University of Palermo, Italy |
Mediterranean diet and longevity in Sicily: a survey in Sicani mountain population |
| 15:00 | Yuliya Yantsen Nazarbayev University, Kazakhstan |
The integrated biomarkers and systemic targets for clinical use of anti-aging regulatory programs |
| 15:15 | Vladimir Stoyanov Anti Aging Center |
Anti aging oligos 5'-(TTAGGG)n-3' treatment maintaining telomere length in vitro in human skin cells overcoming senescence and the t-loop deletion factor |
| 15:30 | Gilad Lehmann Ben-Gurion University of the Negev, Israel |
Back to the Temperature |
| 15:45 | Valeriy Golub Laboratory of Zoological Production, Cherkasy, Ukraine |
The circadian clock conducts development in mammals: Can stopping it be a means of control over aging? |
| 16:00 | Hagai Yanai Ben-Gurion University of the Negev, Israel |
Is Accelerated Wound Healing Good for Longevity? |
| 16:15 | Coffee | |
| Session 17 Longer-term technologies against aging | ||
| 16:30 | Matti Mintz Tel Aviv University, Israel |
A biomimetic model aimed at recovering learning in a brain damaged animal: Converging neuroscience with technology |
| 17:00 | Ben Goertzel Singularity Institute for Artificial Intelligence, USA |
AI Against Aging: The present and future role of AI and AGI in longevity research |
| 17:30 | Max More Alcor |
Cryonic Life Extension |
| 18:00 | Ben Best Cryonics Institute |
Vascular and Neuronal Damage in Cryonics Patients |
| 18:15 | Coffee | |
| Session 18 The long-term context of truly effective medicine aginst aging | ||
| 18:30 | Pierre-Carl Michaud U. Southern California |
The Health, Mortality, and Economic Impacts of Decelerated Aging |
| 19:00 | Jennifer Donohue Cadwalader, Wickersham & Taft, USA |
... Elegant elegans, Black-Scholes, alchemists and flat earthers...! Biology, longevity risk and their economic effects... |
| 19:30 | Mike Kope SENS Foundation |
SENS Foundation and the Rise of Rejuvenation Biotechnology |
| 20:00 | Gala Dinner | |
| Sunday 4th September | ||
| 08:00 | Breakfast | |
| 09:30 | Punting on the River Cam | |
| 11:30 | Conference adjourns | |
| Thank you for your attendance and participation! | ||