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The 300 
For less than the cost of a cup of coffee... you can join a unique group who believe we must push harder for real anti-aging medicine.
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What We AreThe Methuselah Foundation is a non-profit 501(c)(3) volunteer-driven organization founded by U.S. philanthropist David Gobel and Chief Scientist Dr. Aubrey de Grey in 2003 in response to the need for and growing possibility of new treatments for age-related dysfunction and disease. We perform research focused on repairing the molecular damage that accumulates with time at the root of age-related pathologies, and offer the multi-million dollar Methuselah Mouse Prize (Mprize) to spur discovery for new intervention-oriented aging therapies. What We Do - by Aubrey De GreyOur mission is to expedite the development of a true cure for human aging. In my view, the main obstacle to developing such technology is the position of biogerontology at the boundary between basic science and medicine: the fundamental knowledge necessary to develop truly effective anti-aging medicine mostly exists, but the goal-directed frame of mind that is best suited to turning research findings into tools is very different from the curiosity-driven ethos that generated those findings in the first place. SENS is a detailed plan for curing human aging. SENS is an engineering project, recognising that aging is a medical condition and that medicine is a branch of engineering. Aging is a set of progressive changes in body composition, at the molecular and cellular level, which are side-effects of essential metabolic processes. Many of these changes are eventually bad for us -- they are an accumulation of damage, which becomes pathogenic above a certain threshold of abundance. The traditional gerontological approach to life extension is to try to slow down this accumulation of damage. This is a misguided strategy, firstly because it requires us to improve biological processes that we do not adequately understand, and secondly because it can even in principle only retard aging rather than reverse it. An even more short-termist alternative is the geriatric approach, which is to try to stave off pathology in the face of accumulating damage; this is a losing battle because the continuing accumulation of damage makes pathology more and more inescapable. |
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